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| Millions of Ebola vaccine doses by end of 2015 | |
| (35 minutes later) | |
| Millions of doses of an experimental Ebola vaccine will be produced by the end of 2015, the World Health Organization has announced. | |
| It said "several hundred thousand" would be produced in the first half of the year. | It said "several hundred thousand" would be produced in the first half of the year. |
| And vaccines could be offered to health workers on the frontline in West Africa as soon as December 2014. | And vaccines could be offered to health workers on the frontline in West Africa as soon as December 2014. |
| However, the WHO cautioned that vaccines would not be a "magic bullet" for ending the outbreak. | However, the WHO cautioned that vaccines would not be a "magic bullet" for ending the outbreak. |
| There is no proven cure or vaccine for Ebola. | There is no proven cure or vaccine for Ebola. |
| In response to the largest epidemic of the disease in history, the WHO is accelerating the process of vaccine development | In response to the largest epidemic of the disease in history, the WHO is accelerating the process of vaccine development |
| It normally takes years to produce and test a vaccine, but drug manufacturers are now working on a scale of weeks. | It normally takes years to produce and test a vaccine, but drug manufacturers are now working on a scale of weeks. |
| More Ebola cases | |
| The government in Mali has confirmed the first case of Ebola in the country. | |
| A two-year-old girl tested positive for the virus after returned from neighbouring Guinea. | |
| Meanwhile a doctor in New York, who has also returned from Guinea, is in hospital with the virus. | |
| Dr Craig Spencer came down with a fever on Thursday, days after his return, officials say. | |
| Correct dose | Correct dose |
| Two experimental vaccines, produced by GlaxoSmithKline (GSK) and the Public Health Agency of Canada, are already in safety trials. | Two experimental vaccines, produced by GlaxoSmithKline (GSK) and the Public Health Agency of Canada, are already in safety trials. |
| The GSK vaccine is being tested in Mali, the UK and the US. Research on the Canadian vaccine is also under way in the US with further trials expected to start in Europe and Africa soon. | The GSK vaccine is being tested in Mali, the UK and the US. Research on the Canadian vaccine is also under way in the US with further trials expected to start in Europe and Africa soon. |
| The results are expected in December. After that, trials will move to countries affected by Ebola, probably starting with Liberia. | The results are expected in December. After that, trials will move to countries affected by Ebola, probably starting with Liberia. |
| That will allow researchers to assess how effective the vaccine is and what dose is needed to provide protection. | That will allow researchers to assess how effective the vaccine is and what dose is needed to provide protection. |
| Healthcare workers, who place themselves at risk when treating patients, will take part in the first trials in West Africa. | Healthcare workers, who place themselves at risk when treating patients, will take part in the first trials in West Africa. |
| The WHO says we should have the first hints of how effective these experimental vaccines are by April. | The WHO says we should have the first hints of how effective these experimental vaccines are by April. |
| There are no plans for mass vaccination before June 2015 but the WHO has not ruled it out. | There are no plans for mass vaccination before June 2015 but the WHO has not ruled it out. |
| The WHO says vaccines are likely to be key to ending the outbreak, even if cases fall in the next few months. | The WHO says vaccines are likely to be key to ending the outbreak, even if cases fall in the next few months. |
| 'Prudent to prepare' | 'Prudent to prepare' |
| Dr Marie Paule Kieny, a WHO assistant director-general, said: "While we hope that the massive response, which has been put in place will have an impact on the epidemic, it is still prudent to prepare to have as much vaccine available as possible if they are proven effective. | Dr Marie Paule Kieny, a WHO assistant director-general, said: "While we hope that the massive response, which has been put in place will have an impact on the epidemic, it is still prudent to prepare to have as much vaccine available as possible if they are proven effective. |
| "If the massive effort in response is not sufficient, then vaccine would be a very important tool. | "If the massive effort in response is not sufficient, then vaccine would be a very important tool. |
| "And even if the epidemic would be already receding by the time we have vaccine available, the modelling seems to say vaccine may still have an impact on controlling the epidemic." | "And even if the epidemic would be already receding by the time we have vaccine available, the modelling seems to say vaccine may still have an impact on controlling the epidemic." |
| The vaccine plan was the culmination of a day of talks at the WHO in Geneva. | |
| As well as the two vaccines already in trials, there are a further five in the pipeline which could yet play a role in the outbreak. | As well as the two vaccines already in trials, there are a further five in the pipeline which could yet play a role in the outbreak. |
| The World Bank and the charity Medecins Sans Frontieres will help finance the vaccine. | The World Bank and the charity Medecins Sans Frontieres will help finance the vaccine. |
| Dr Marta Tufet, from the Wellcome Trust and part of the talks in Geneva, told the BBC News website: "I think we've made some majors steps forward, it's been a very significant meeting. | |
| "The key news is that money doesn't seem to be an issue, everyone's supporting this and it's a case of making sure we're prepared. | |
| "The standard method of public health control will win in the end, but a vaccine could have a very strong impact on the current epidemic." | |
| There are also suggestions that an "indemnity fund" could be set up in case people have a serious adverse reaction to a vaccine being rushed through. | There are also suggestions that an "indemnity fund" could be set up in case people have a serious adverse reaction to a vaccine being rushed through. |
| But until a vaccine is found to prevent the virus from spreading, treating and isolating sufferers will remain the key strategy for containing the outbreak. | But until a vaccine is found to prevent the virus from spreading, treating and isolating sufferers will remain the key strategy for containing the outbreak. |
| Big risk | Big risk |
| Jonathan Ball, a professor of virology at the University of Nottingham, commented: "This is a big risk because we simply don't know if the vaccines will work. | Jonathan Ball, a professor of virology at the University of Nottingham, commented: "This is a big risk because we simply don't know if the vaccines will work. |
| "But clearly, given the scale of problem in Africa, a problem that has arisen through international apathy, we are having to prepare for the worse." | "But clearly, given the scale of problem in Africa, a problem that has arisen through international apathy, we are having to prepare for the worse." |
| He added that it would be difficult to deliver the vaccine - which needs to be stored at very low temperatures - would be a major challenge in Africa. | He added that it would be difficult to deliver the vaccine - which needs to be stored at very low temperatures - would be a major challenge in Africa. |
| Dr Benjamin Neuman, from the University of Reading, told the BBC: "I very much hope that the current outbreak will be over before the first vaccines ship, but even so, a vaccine will be important to long-term plans to prevent an Ebola outbreak on this scale from ever happening again." | Dr Benjamin Neuman, from the University of Reading, told the BBC: "I very much hope that the current outbreak will be over before the first vaccines ship, but even so, a vaccine will be important to long-term plans to prevent an Ebola outbreak on this scale from ever happening again." |
| He said there were many "similarly frightening and incurable viruses" across Europe and the Americas but they were contained by infrastructure. | He said there were many "similarly frightening and incurable viruses" across Europe and the Americas but they were contained by infrastructure. |
| He said that for all the talk of vaccines: "The closest thing to a magic bullet that stops all diseases is still a hospital." | He said that for all the talk of vaccines: "The closest thing to a magic bullet that stops all diseases is still a hospital." |
| Have you been affected by the issues raised in this article? You can share your experience by emailing haveyoursay@bbc.co.uk | Have you been affected by the issues raised in this article? You can share your experience by emailing haveyoursay@bbc.co.uk |
| Ebola virus disease (EVD) | |
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