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A virus hunter faces the big one: Ebola	A virus hunter faces the big one: Ebola
2014-09-14 23:51:02 UTC	2014-09-15 03:50:53 UTC (about 4 hours later)
FREETOWN, Sierra Leone — Joseph Fair hunts viruses. That’s his thing. The 37-year-old American loves chasing dangerous pathogens, studying them in secure labs or searching for them in jungles where the microbes lurk.	FREETOWN, Sierra Leone — Joseph Fair hunts viruses. That’s his thing. The 37-year-old American loves chasing dangerous pathogens, studying them in secure labs or searching for them in jungles where the microbes lurk.
And one virus has always loomed as the big one — Ebola. The scientists who first chased this dreaded microbe back in the ’80s and ’90s became legends, inspiring a generation of virologists like Fair. He read their books and papers. He studied how they contained the pathogen’s spread. And the scientists always won. The outbreaks ended, Ebola driven away.	And one virus has always loomed as the big one — Ebola. The scientists who first chased this dreaded microbe back in the ’80s and ’90s became legends, inspiring a generation of virologists like Fair. He read their books and papers. He studied how they contained the pathogen’s spread. And the scientists always won. The outbreaks ended, Ebola driven away.
So when the call came in March to travel to Sierra Leone, Fair was excited. He loved Mama Salone, as locals know the nation. He’d worked here for years. His new job: to advise Sierra Leone’s government on a tiny Ebola outbreak in neighboring Guinea, at the behest of the U.S. Defense Department. He set up an Ebola emergency operations center. He trained medical staff. He drew up just-in-case plans. By mid-May, the outbreak seemed on its way out. Fair packed his bags and left.	So when the call came in March to travel to Sierra Leone, Fair was excited. He loved Mama Salone, as locals know the nation. He’d worked here for years. His new job: to advise Sierra Leone’s government on a tiny Ebola outbreak in neighboring Guinea, at the behest of the U.S. Defense Department. He set up an Ebola emergency operations center. He trained medical staff. He drew up just-in-case plans. By mid-May, the outbreak seemed on its way out. Fair packed his bags and left.
Then Ebola exploded.	Then Ebola exploded.
Now, Fair is back in West Africa, in the middle of the worst Ebola outbreak in history. A viral epidemic. The world’s ability to respond is stretched. Plans are being devised on the fly.	Now, Fair is back in West Africa, in the middle of the worst Ebola outbreak in history. A viral epidemic. The world’s ability to respond is stretched. Plans are being devised on the fly.
“This is the big one no one expected,” Fair says.	“This is the big one no one expected,” Fair says.
It has been a humbling time. Fair has worked seven days a week, hunting for ways to curb the outbreak, at times begging international groups for staff and supplies. He is exhausted. He’s put on 15 pounds. He sent his girlfriend home to California months ago. Too dangerous here, he told her. He’s seen Sierra Leonean doctors and nurses — friends he’s known for years — get infected and die. He sweated out his own Ebola scare.	It has been a humbling time. Fair has worked seven days a week, hunting for ways to curb the outbreak, at times begging international groups for staff and supplies. He is exhausted. He’s put on 15 pounds. He sent his girlfriend home to California months ago. Too dangerous here, he told her. He’s seen Sierra Leonean doctors and nurses — friends he’s known for years — get infected and die. He sweated out his own Ebola scare.
“It’s like he was trying single-handedly to stop this outbreak,” says Randal Schoepp, chief of the U.S. Army’s applied diagnostics branch at Fort Detrick, Md., who has worked with Fair in West Africa.	“It’s like he was trying single-handedly to stop this outbreak,” says Randal Schoepp, chief of the U.S. Army’s applied diagnostics branch at Fort Detrick, Md., who has worked with Fair in West Africa.
But the number of new Ebola cases has just kept shooting higher, like an unbreakable fever.	But the number of new Ebola cases has just kept shooting higher, like an unbreakable fever.
For Fair and other scientists, this has not felt like failure. It is more complicated than that.	For Fair and other scientists, this has not felt like failure. It is more complicated than that.
“As bad as it has been,” observes Connie Schmaljohn, senior research scientist at the Army’s Medical Research Institute of Infectious Diseases, “it could’ve been worse if people like Joseph hadn’t been there.”	“As bad as it has been,” observes Connie Schmaljohn, senior research scientist at the Army’s Medical Research Institute of Infectious Diseases, “it could’ve been worse if people like Joseph hadn’t been there.”
Now, Fair is taking a rare break. He is sitting on the outdoor deck at a hotel where U.N. peacekeepers used to live after this country’s long civil war. The Mammy Yoko today is filled with aid workers and doctors. Fair wears a black T-shirt and blue jeans, his blonde hair going gray near the temples. He is nursing a double shot of whiskey, a nod to both his eastern Kentucky roots and his mounting stress.	Now, Fair is taking a rare break. He is sitting on the outdoor deck at a hotel where U.N. peacekeepers used to live after this country’s long civil war. The Mammy Yoko today is filled with aid workers and doctors. Fair wears a black T-shirt and blue jeans, his blonde hair going gray near the temples. He is nursing a double shot of whiskey, a nod to both his eastern Kentucky roots and his mounting stress.
The son of a nurse and a college professor, Fair grew up with dreams of being a missionary. He wanted to help people. In college at Loyola University New Orleans, he read “Virus Hunter,” about famed virologist C.J. Peters’s career chasing Ebola and other pathogens. Fair discovered a new calling. A few years later, he was working at Peters’s lab at the University of Texas Medical Branch in Galveston. Peters recalls how Fair volunteered to work with hot viruses in the highest-security labs.	The son of a nurse and a college professor, Fair grew up with dreams of being a missionary. He wanted to help people. In college at Loyola University New Orleans, he read “Virus Hunter,” about famed virologist C.J. Peters’s career chasing Ebola and other pathogens. Fair discovered a new calling. A few years later, he was working at Peters’s lab at the University of Texas Medical Branch in Galveston. Peters recalls how Fair volunteered to work with hot viruses in the highest-security labs.
~~“That indicated right ~~way~~ that he was going to do things,” Peters recalls. “It’s been gratifying to see him take up the cudgel.”~~	“That indicated right away that he was going to do things,” Peters recalls. “It’s been gratifying to see him take up the cudgel.”
Now, on the hotel deck, another famed Ebola hunter sits at a nearby table. Tom Ksiazek was recently tapped by the Centers for Disease Control and Prevention to help in Sierra Leone. He and Fair work together at the Ebola emergency operations center.	Now, on the hotel deck, another famed Ebola hunter sits at a nearby table. Tom Ksiazek was recently tapped by the Centers for Disease Control and Prevention to help in Sierra Leone. He and Fair work together at the Ebola emergency operations center.
“A CDC legend,” Fair says with admiration after Ksiazek stops by to say hello.	“A CDC legend,” Fair says with admiration after Ksiazek stops by to say hello.
In a far corner, a group gathers to welcome the new World Health Organization representative in Sierra Leone. The previous one had been shipped home. The WHO blames exhaustion. But many here see it differently.	In a far corner, a group gathers to welcome the new World Health Organization representative in Sierra Leone. The previous one had been shipped home. The WHO blames exhaustion. But many here see it differently.
“Someone has to take the fall when things go like this,” Fair says.	“Someone has to take the fall when things go like this,” Fair says.
“Like this” would be the criticism that the WHO and other international groups were slow to respond to the tragedy in West Africa. Governments are under pressure, too. Liberia’s government could fall. Sierra Leone’s health minister, who was officially directing the national Ebola response, lost her job last month.	“Like this” would be the criticism that the WHO and other international groups were slow to respond to the tragedy in West Africa. Governments are under pressure, too. Liberia’s government could fall. Sierra Leone’s health minister, who was officially directing the national Ebola response, lost her job last month.
But no one expected this epidemic. No one anticipated that Ebola — a disease with no cure and a 21-day incubation period that is spread through close contact with blood, saliva or sweat — would sweep into urban areas, especially in West Africa. Every previous outbreak occurred in remote settings.	But no one expected this epidemic. No one anticipated that Ebola — a disease with no cure and a 21-day incubation period that is spread through close contact with blood, saliva or sweat — would sweep into urban areas, especially in West Africa. Every previous outbreak occurred in remote settings.
“You’d like to think someone was thinking about this all along,” Fair says. “But not so much.”	“You’d like to think someone was thinking about this all along,” Fair says. “But not so much.”
In 2012, Fair gave a talk that seemed to foreshadow the current crisis. He was working for a company that aimed to head off pandemics, such as H1N1 flu and SARS. At San Francisco-based Metabiota, formerly called Global Viral Forecasting, founded by well-known virus hunter Nathan Wolfe, Fair conducted lots of medical diplomacy work for the U.S. government.	In 2012, Fair gave a talk that seemed to foreshadow the current crisis. He was working for a company that aimed to head off pandemics, such as the H1N1 flu and SARS. At San Francisco-based Metabiota, formerly called Global Viral Forecasting, founded by well-known virus hunter Nathan Wolfe, Fair conducted lots of medical diplomacy work for the U.S. government.
In that talk at the World Vaccine Congress, Fair warned about delays in tackling viral outbreaks. “We truly have a political problem when it comes to responding to these diseases,” he said.	In that talk at the World Vaccine Congress, Fair warned about delays in tackling viral outbreaks. “We truly have a political problem when it comes to responding to these diseases,” he said.
So it seemed like a good sign when Fair was dispatched to Sierra Leone in late March before even the first Ebola diagnosis was made. The WHO had asked for his help. The Defense Department sent him — more medical diplomacy. Guinea was investigating 49 cases of an unknown hemorrhagic fever.	So it seemed like a good sign when Fair was dispatched to Sierra Leone in late March before even the first Ebola diagnosis was made. The WHO had asked for his help. The Defense Department sent him — more medical diplomacy. Guinea was investigating 49 cases of an unknown hemorrhagic fever.
Fair knew Sierra Leone from his work at a U.S.-funded lab that focused on Lassa fever, a hemorrhagic fever similar to Ebola, but spread by rats. The small lab in the eastern city of Kenema was the county’s most advanced, the only one capable of testing for Ebola.	Fair knew Sierra Leone from his work at a U.S.-funded lab that focused on Lassa fever, a hemorrhagic fever similar to Ebola, but spread by rats. The small lab in the eastern city of Kenema was the county’s most advanced, the only one capable of testing for Ebola.
Before he could get settled, Guinea’s mystery illness was confirmed as the dreaded Ebola.	Before he could get settled, Guinea’s mystery illness was confirmed as the dreaded Ebola.
Fair and others raced to face an Ebola outbreak expected to spill across borders. Hospital staff were taught to look for the high fevers and weakness of suspected Ebola sufferers. Isolation wards were set up. Medical surveillance teams were trained to track infections. Rubber boots, bleach and thermometers were distributed. A national media campaign was launched to introduce 6 million people to a disease never seen before in Sierra Leone.	Fair and others raced to face an Ebola outbreak expected to spill across borders. Hospital staff were taught to look for the high fevers and weakness of suspected Ebola sufferers. Isolation wards were set up. Medical surveillance teams were trained to track infections. Rubber boots, bleach and thermometers were distributed. A national media campaign was launched to introduce 6 million people to a disease never seen before in Sierra Leone.
“There were a lot of people in denial that it was real,” Fair says.	“There were a lot of people in denial that it was real,” Fair says.
And he waited. April turned to May. Hundreds of people with Ebola symptoms were tested: Nothing. Not a single case. Guinea and Liberia were quiet, too. Aid groups such as Doctors Without ~~Borderswere~~ optimistic. The WHO declared the outbreak, after about 260 cases, “stable.”	And he waited. April turned to May. Hundreds of people with Ebola symptoms were tested: Nothing. Not a single case. Guinea and Liberia were quiet, too. Aid groups such as Doctors Without Borders were optimistic. The WHO declared the outbreak, after about 260 cases, “stable.”
Scientists consider an Ebola outbreak extinguished if no new cases are detected after 42 days — the length of two incubation periods. That vital deadline approached in the last week of May.	Scientists consider an Ebola outbreak extinguished if no new cases are detected after 42 days — the length of two incubation periods. That vital deadline approached in the last week of May.
Fair flew to Paris. He was burned ~~out.He’d~~ been hustling for weeks. He’d broken with Metabiota and was heading out on his own. Then, on May 25, he received an e-mail from the WHO: Ebola was back.	Fair flew to Paris. He was burned out. He’d been hustling for weeks. He’d broken with Metabiota and was heading out on his own. Then, on May 25, he received an e-mail from the WHO: Ebola was back.
New cases were reported in Guinea and Liberia, plus Sierra Leone. Fair was stunned. They had been so close. He wanted to return to Mama Salone. A couple of weeks later, the Defense Department asked him to go back. They couldn’t pay him, but they could cobble together enough funding to cover his flights, a small per diem and his health insurance.	New cases were reported in Guinea and Liberia, plus Sierra Leone. Fair was stunned. They had been so close. He wanted to return to Mama Salone. A couple of weeks later, the Defense Department asked him to go back. They couldn’t pay him, but they could cobble together enough funding to cover his flights, a small per diem and his health insurance.
He returned in early July. He set out to Kenema, a four-hour drive from Freetown, to visit his close friend Sheik Humarr Khan, a virologist who ran the Lassa lab and was now caring for Ebola patients. Fair delivered fresh supplies of biohazard suits and gloves. He hugged and kissed the hospital’s head nurse, Mbalu Sankoh.	He returned in early July. He set out to Kenema, a four-hour drive from Freetown, to visit his close friend Sheik Humarr Khan, a virologist who ran the Lassa lab and was now caring for Ebola patients. Fair delivered fresh supplies of biohazard suits and gloves. He hugged and kissed the hospital’s head nurse, Mbalu Sankoh.
Days later, Sankoh developed a fever. It was Ebola. Fair had been exposed. He spent three weeks wondering if he felt hot, wondering if every ache was a sign of a raging infection.	Days later, Sankoh developed a fever. It was Ebola. Fair had been exposed. He spent three weeks wondering if he felt hot, wondering if every ache was a sign of a raging infection.
He was lucky. But Khan contracted Ebola. Forty hospital staff in Kenema ended up being infected. The Ebola ward was overwhelmed. When Khan died July 29, the nation was stunned. He was hailed as a national hero. But people’s confidence was rattled. And the preparations for handling the Ebola outbreak, already teetering, collapsed.	He was lucky. But Khan contracted Ebola. Forty hospital staff in Kenema ended up being infected. The Ebola ward was overwhelmed. When Khan died July 29, the nation was stunned. He was hailed as a national hero. But people’s confidence was rattled. And the preparations for handling the Ebola outbreak, already teetering, collapsed.
“That all went to pot because everyone freaked out,” Fair says.	“That all went to pot because everyone freaked out,” Fair says.
Hospitals shut down. Nurses refused to work. People became afraid to admit they were showing signs of Ebola, leading to more infections. Fair felt the world was ignoring the seriousness of the outbreak. He pleaded for more biohazard suits, rubber gloves, cellphone cards for staff trying to trace Ebola contacts, fuel for cars used by Ebola surveillance teams. He’d request field epidemiologists to track the outbreak in far-flung provinces. He got data epidemiologists to sit in offices. He spent days on the phone trying to just source ambulances equipped with dividers between the front and back.	Hospitals shut down. Nurses refused to work. People became afraid to admit they were showing signs of Ebola, leading to more infections. Fair felt the world was ignoring the seriousness of the outbreak. He pleaded for more biohazard suits, rubber gloves, cellphone cards for staff trying to trace Ebola contacts, fuel for cars used by Ebola surveillance teams. He’d request field epidemiologists to track the outbreak in far-flung provinces. He got data epidemiologists to sit in offices. He spent days on the phone trying just to source ambulances equipped with dividers between the front and back.
“We were pretty much isolated teams functioning on the basics,” Fair says.	“We were pretty much isolated teams functioning on the basics,” Fair says.