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Vitamin D 'may help slow ageing' | Vitamin D 'may help slow ageing' |
(1 day later) | |
A vitamin made when sunlight hits the skin could help slow down the ageing of cells and tissues, say researchers. | A vitamin made when sunlight hits the skin could help slow down the ageing of cells and tissues, say researchers. |
A King's College London study of more than 2,000 women found those with higher vitamin D levels showed fewer ageing-related changes in their DNA. | A King's College London study of more than 2,000 women found those with higher vitamin D levels showed fewer ageing-related changes in their DNA. |
However, the American Journal of Clinical Nutrition study stops short of proving cause and effect. | However, the American Journal of Clinical Nutrition study stops short of proving cause and effect. |
A lack of vitamin D, also found in some foods, has also been linked to multiple sclerosis and rheumatoid arthritis. | |
It's possible that the same sunshine which may increase our risk of skin cancer may also have a healthy effect on the ageing process in general Professor Tim SpectorKing's College London | It's possible that the same sunshine which may increase our risk of skin cancer may also have a healthy effect on the ageing process in general Professor Tim SpectorKing's College London |
The genetic material inside every cell has an inbuilt "clock", which counts down every time the cell reproduces itself. | The genetic material inside every cell has an inbuilt "clock", which counts down every time the cell reproduces itself. |
The shortening of these strands of DNA called telomeres is one way of examining the ageing process at a cellular level. | The shortening of these strands of DNA called telomeres is one way of examining the ageing process at a cellular level. |
Snapshot measurement | Snapshot measurement |
The King's team looked at white blood cells, which tend to experience faster rates of turnover - and faster shortening of telomeres - when the body's tissues are suffering more inflammation. | The King's team looked at white blood cells, which tend to experience faster rates of turnover - and faster shortening of telomeres - when the body's tissues are suffering more inflammation. |
They looked at a total of 2,160 women aged between 18 and 79, and took a snapshot measurement of the levels of vitamin D in their bloodstream, comparing this to the length of the telomeres in their white blood cells. | They looked at a total of 2,160 women aged between 18 and 79, and took a snapshot measurement of the levels of vitamin D in their bloodstream, comparing this to the length of the telomeres in their white blood cells. |
They found that, after adjusting the results for the age of the volunteer, women with higher levels of vitamin D were more likely to have longer telomeres in these cells, and vice versa. | They found that, after adjusting the results for the age of the volunteer, women with higher levels of vitamin D were more likely to have longer telomeres in these cells, and vice versa. |
What we do know is that while telomere length can be used as a biological marker, for an individual, it is not a very precise one Professor Thomas von ZglinickiNewcastle University | What we do know is that while telomere length can be used as a biological marker, for an individual, it is not a very precise one Professor Thomas von ZglinickiNewcastle University |
Professor Brent Richards, who led the study, said: "These results are exciting because they demonstrate for the first time that people who have higher levels of vitamin D may age more slowly than people with lower levels of vitamin D. | Professor Brent Richards, who led the study, said: "These results are exciting because they demonstrate for the first time that people who have higher levels of vitamin D may age more slowly than people with lower levels of vitamin D. |
"This could help to explain how vitamin D has a protective effect on many ageing-related diseases, such as heart disease and cancer." | "This could help to explain how vitamin D has a protective effect on many ageing-related diseases, such as heart disease and cancer." |
Another of the study's authors, Professor Tim Spector, said: "Although it might sound absurd, it's possible that the same sunshine which may increase our risk of skin cancer may also have a healthy effect on the ageing process in general." | Another of the study's authors, Professor Tim Spector, said: "Although it might sound absurd, it's possible that the same sunshine which may increase our risk of skin cancer may also have a healthy effect on the ageing process in general." |
No proof | No proof |
The study authors, however, conceded that while this suggested a link between vitamin D levels and telomere length, it did not provide unequivocal evidence that vitamin D was responsible for this effect, rather than some other factor unaccounted for in the research,. | The study authors, however, conceded that while this suggested a link between vitamin D levels and telomere length, it did not provide unequivocal evidence that vitamin D was responsible for this effect, rather than some other factor unaccounted for in the research,. |
Professor Thomas von Zglinicki, a leading telomere researcher from the University of Newcastle, said that this was more evidence that telomere length could be related to ageing and age-related diseases. | Professor Thomas von Zglinicki, a leading telomere researcher from the University of Newcastle, said that this was more evidence that telomere length could be related to ageing and age-related diseases. |
However, he said: "What we do know is that while telomere length can be used as a biological marker, for an individual, it is not a very precise one. | However, he said: "What we do know is that while telomere length can be used as a biological marker, for an individual, it is not a very precise one. |
"Other studies have found that people who die at the same age can have significant differences in their telomere length - up to 30 times the differences described in this study. | "Other studies have found that people who die at the same age can have significant differences in their telomere length - up to 30 times the differences described in this study. |
"We just still don't know how all the different factors that correlate to telomere length work together." | "We just still don't know how all the different factors that correlate to telomere length work together." |
He said that it was possible that vitamin D might not be delaying the shortening of telomeres, but that another factor which did this might alter the way the vitamin was created and metabolised by the body. | He said that it was possible that vitamin D might not be delaying the shortening of telomeres, but that another factor which did this might alter the way the vitamin was created and metabolised by the body. |
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