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Lab rats 'acquire sixth sense' | Lab rats 'acquire sixth sense' |
(about 4 hours later) | |
US researchers have effectively given laboratory rats a "sixth sense" using an implant in their brains. | US researchers have effectively given laboratory rats a "sixth sense" using an implant in their brains. |
An experimental device allowed the rats to "touch" infrared light - which is normally invisible to them. | An experimental device allowed the rats to "touch" infrared light - which is normally invisible to them. |
The team at Duke University fitted the rats with an infrared detector wired up to microscopic electrodes that were implanted in the part of their brains that processes tactile information. | The team at Duke University fitted the rats with an infrared detector wired up to microscopic electrodes that were implanted in the part of their brains that processes tactile information. |
The results of the study were published in Nature Communications journal. | The results of the study were published in Nature Communications journal. |
The researchers say that, in theory at least, a human with a damaged visual cortex might be able to regain sight through a device implanted in another part of the brain. | The researchers say that, in theory at least, a human with a damaged visual cortex might be able to regain sight through a device implanted in another part of the brain. |
Lead author Miguel Nicolelis said this was the first time a brain-machine interface has augmented a sense in adult animals. | Lead author Miguel Nicolelis said this was the first time a brain-machine interface has augmented a sense in adult animals. |
The experiment also shows that a new sensory input can be interpreted by a region of the brain that normally does something else (without having to "hijack" the function of that brain region). | The experiment also shows that a new sensory input can be interpreted by a region of the brain that normally does something else (without having to "hijack" the function of that brain region). |
"We could create devices sensitive to any physical energy," said Prof Nicolelis, from the Duke University Medical Center in Durham, North Carolina. | "We could create devices sensitive to any physical energy," said Prof Nicolelis, from the Duke University Medical Center in Durham, North Carolina. |
"It could be magnetic fields, radio waves, or ultrasound. We chose infrared initially because it didn't interfere with our electrophysiological recordings." | "It could be magnetic fields, radio waves, or ultrasound. We chose infrared initially because it didn't interfere with our electrophysiological recordings." |
Brain training | Brain training |
His colleague Eric Thomson commented: "The philosophy of the field of brain-machine interfaces has until now been to attempt to restore a motor function lost to lesion or damage of the central nervous system. | His colleague Eric Thomson commented: "The philosophy of the field of brain-machine interfaces has until now been to attempt to restore a motor function lost to lesion or damage of the central nervous system. |
"This is the first paper in which a neuroprosthetic device was used to augment function - literally enabling a normal animal to acquire a sixth sense." | "This is the first paper in which a neuroprosthetic device was used to augment function - literally enabling a normal animal to acquire a sixth sense." |
In their experiments, the researchers used a test chamber with three light sources that could be switched on randomly. | In their experiments, the researchers used a test chamber with three light sources that could be switched on randomly. |
They taught the rats to choose the active light source by poking their noses into a port to receive a sip of water as a reward. They then implanted the microelectrodes, each about a tenth the diameter of a human hair, into the animals' brains. These electrodes were attached to the infrared detectors. | They taught the rats to choose the active light source by poking their noses into a port to receive a sip of water as a reward. They then implanted the microelectrodes, each about a tenth the diameter of a human hair, into the animals' brains. These electrodes were attached to the infrared detectors. |
The scientists then returned the animals to the test chamber. At first, the rats scratched at their faces, indicating that they were interpreting the lights as touch. But after a month - as shown in href="http://www.nicolelislab.net/?p=345" >these videos - the animals learned to associate the signal in their brains with the infrared source. | |
They began to search actively for the signal, eventually achieving perfect scores in tracking and identifying the correct location of the invisible light source. | They began to search actively for the signal, eventually achieving perfect scores in tracking and identifying the correct location of the invisible light source. |
One key finding was that enlisting the touch cortex to detect infrared light did not reduce its ability to process touch signals. | One key finding was that enlisting the touch cortex to detect infrared light did not reduce its ability to process touch signals. |
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