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Vitamin D 'may help ward off TB' | Vitamin D 'may help ward off TB' |
(about 5 hours later) | |
A dose of vitamin D may help ward off tuberculosis, research suggests. | A dose of vitamin D may help ward off tuberculosis, research suggests. |
A study of 131 people found the vitamin helped to boost the ability of the body to inhibit the growth of bacteria that causes the respiratory disease. | A study of 131 people found the vitamin helped to boost the ability of the body to inhibit the growth of bacteria that causes the respiratory disease. |
Researchers from Queen Mary's School of Medicine and Imperial College said it could be used to target at-risk patients or added to drinks. | Researchers from Queen Mary's School of Medicine and Imperial College said it could be used to target at-risk patients or added to drinks. |
The study appeared in the American Journal of Respiratory and Critical Care Medicine. | The study appeared in the American Journal of Respiratory and Critical Care Medicine. |
Vitamin D was originally used to treat TB in sanatoriums before antibiotics came in to use. | Vitamin D was originally used to treat TB in sanatoriums before antibiotics came in to use. |
What makes this potentially a very good intervention is that it is cheap and easy to administer Professor Peter Davies, a chest specialist | What makes this potentially a very good intervention is that it is cheap and easy to administer Professor Peter Davies, a chest specialist |
But until now no study has evaluated the effect of vitamin D on the body's immunity to mycobacteria, the family of bacteria that cause TB. | But until now no study has evaluated the effect of vitamin D on the body's immunity to mycobacteria, the family of bacteria that cause TB. |
During the study, blood was taken from all the participants and infected with mycobacteria. | During the study, blood was taken from all the participants and infected with mycobacteria. |
The group was then split into two with 64 given a dummy pill and the rest a 2.5mg dose of vitamin D. | The group was then split into two with 64 given a dummy pill and the rest a 2.5mg dose of vitamin D. |
After six weeks, blood was taken again and infected with mycobacteria. | After six weeks, blood was taken again and infected with mycobacteria. |
The samples of blood were analysed after 24 hours, and the growth of the samples taken from people given vitamin D was 20% less than the placebo group. | The samples of blood were analysed after 24 hours, and the growth of the samples taken from people given vitamin D was 20% less than the placebo group. |
The researchers said clinical trials were now needed to fully prove the findings, but they added the vitamin had the potential to help ward off the respiratory disease. | The researchers said clinical trials were now needed to fully prove the findings, but they added the vitamin had the potential to help ward off the respiratory disease. |
They said it could be given to those deemed at risk - the bacteria can lie dormant waiting for the immune system to be weakened before striking - or added to drinks such as milk and orange juice. | |
Rise | Rise |
It comes as TB rose by 2% last year to over 8,000 new cases in England, Wales and Northern Ireland. | It comes as TB rose by 2% last year to over 8,000 new cases in England, Wales and Northern Ireland. |
London accounted for nearly half of the cases, with the migrant population identified as the primary source. | London accounted for nearly half of the cases, with the migrant population identified as the primary source. |
TB is also a major global problem, responsible for 2m deaths a year. | TB is also a major global problem, responsible for 2m deaths a year. |
Lead researcher Dr Adrian Martineau added: "This shows that a simple, cheap supplement could make a significant impact on the health of people most at risk from the disease." | Lead researcher Dr Adrian Martineau added: "This shows that a simple, cheap supplement could make a significant impact on the health of people most at risk from the disease." |
Professor Peter Davies, a chest specialist and secretary of the TB Alert campaign group, said: "We have known for a while vitamin D could help and it is good to see it being confirmed in such a study. | Professor Peter Davies, a chest specialist and secretary of the TB Alert campaign group, said: "We have known for a while vitamin D could help and it is good to see it being confirmed in such a study. |
"What makes this potentially a very good intervention is that it is cheap and easy to administer. But we need to await the clinical trials." | "What makes this potentially a very good intervention is that it is cheap and easy to administer. But we need to await the clinical trials." |
The results add to a growing body of evidence about the health benefits of vitamin D - it has also been linked to reducing the risk of cancer and diabetes as well as strengthening the bones. | The results add to a growing body of evidence about the health benefits of vitamin D - it has also been linked to reducing the risk of cancer and diabetes as well as strengthening the bones. |
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