This article is from the source 'bbc' and was first published or seen on . It will not be checked again for changes.
You can find the current article at its original source at http://news.bbc.co.uk/go/rss/-/1/hi/health/6517645.stm
The article has changed 8 times. There is an RSS feed of changes available.
| Version 0 | Version 1 |
|---|---|
| Heart valve grown from stem cells | Heart valve grown from stem cells |
| (about 1 hour later) | |
| British scientists have grown part of a human heart from stem cells for the first time. | British scientists have grown part of a human heart from stem cells for the first time. |
| Heart surgeon Sir Magdi Yacoub, who led the team, said doctors could be using artificially grown heart components in transplants within three years. | Heart surgeon Sir Magdi Yacoub, who led the team, said doctors could be using artificially grown heart components in transplants within three years. |
| His researchers at Harefield hospital managed to grow tissue that works in the same way as human heart valves. | His researchers at Harefield hospital managed to grow tissue that works in the same way as human heart valves. |
| Sir Magdi told the Guardian newspaper a whole heart could be produced from stem cells within 10 years. | Sir Magdi told the Guardian newspaper a whole heart could be produced from stem cells within 10 years. |
| 'Common pathway' | 'Common pathway' |
| The team who spent 10 years working on the project included physicists, pharmacologists, clinicians and cellular scientists. | The team who spent 10 years working on the project included physicists, pharmacologists, clinicians and cellular scientists. |
| You can see the common pathway of death and suffering is heart failure Sir Magdi Yacoub Researchers will see their achievement as a major step towards growing entire organs for transplant. | You can see the common pathway of death and suffering is heart failure Sir Magdi Yacoub Researchers will see their achievement as a major step towards growing entire organs for transplant. |
| Stem cells have the potential to turn into many different types of cell. | Stem cells have the potential to turn into many different types of cell. |
| Many scientists believe it should be possible to harness the cells' ability to grow into different tissues to repair damage and treat disease. | Many scientists believe it should be possible to harness the cells' ability to grow into different tissues to repair damage and treat disease. |
| Previously, scientists have grown tendons, cartilages and bladders, which are all less complex. | Previously, scientists have grown tendons, cartilages and bladders, which are all less complex. |
| Sir Magdi, professor of cardiac surgery at Imperial College London, had been working on ways to address a shortage of donated hearts for patients. | Sir Magdi, professor of cardiac surgery at Imperial College London, had been working on ways to address a shortage of donated hearts for patients. |
| Entire heart hope | Entire heart hope |
| He said he hoped that soon an entire heart could be grown from stem cells. | He said he hoped that soon an entire heart could be grown from stem cells. |
| This is very preliminary work and the direct translation to human is still some way off in the futur Dr Stephen MingerKing's College London | This is very preliminary work and the direct translation to human is still some way off in the futur Dr Stephen MingerKing's College London |
| He added: "It is an ambitious project but not impossible. If you want me to guess I'd say 10 years." | He added: "It is an ambitious project but not impossible. If you want me to guess I'd say 10 years." |
| His team extracted stem cells from bone marrow and cultivated them into heart valve cells. | His team extracted stem cells from bone marrow and cultivated them into heart valve cells. |
| After they were placed in scaffolds formed from collagen, 3cm-wide discs of heart valve tissue were formed. | After they were placed in scaffolds formed from collagen, 3cm-wide discs of heart valve tissue were formed. |
| Later in the year, these will be implanted into animals such as sheep or pigs to see how well they fare. | Later in the year, these will be implanted into animals such as sheep or pigs to see how well they fare. |
| Dr Stephen Minger, a stem cell expert at London's King's College, said Sir Magdi's team were at the forefront of tissue engineering for cardiac disease. | Dr Stephen Minger, a stem cell expert at London's King's College, said Sir Magdi's team were at the forefront of tissue engineering for cardiac disease. |
| "If the valves they've engineered prove successful in experimental animals, this could open the door to generating complex tissues from stem cells for a wide variety of clinical application. | "If the valves they've engineered prove successful in experimental animals, this could open the door to generating complex tissues from stem cells for a wide variety of clinical application. |
| "But as they stress, this is very preliminary work and the direct translation to human is still some way off in the future." | "But as they stress, this is very preliminary work and the direct translation to human is still some way off in the future." |
| Heart disease is the UK's biggest killer. More than 200,000 people died from heart disease and strokes in 2004. | |
| And in 2003 nearly 10,000 people needed surgery to replace heart valves with artificial ones. |