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Heart valve grown from stem cells | Heart valve grown from stem cells |
(about 5 hours later) | |
British scientists have grown part of a human heart from stem cells for the first time. | British scientists have grown part of a human heart from stem cells for the first time. |
Heart surgeon Sir Magdi Yacoub, who led the team, said doctors could be using artificially grown heart components in transplants within three years. | |
His researchers at Harefield hospital managed to grow tissue that works in the same way as human heart valves. | His researchers at Harefield hospital managed to grow tissue that works in the same way as human heart valves. |
Sir Magdi told the Guardian newspaper a whole heart could be produced from stem cells within 10 years. | Sir Magdi told the Guardian newspaper a whole heart could be produced from stem cells within 10 years. |
'Common pathway' | 'Common pathway' |
The team who spent 10 years working on the project included physicists, pharmacologists, clinicians and cellular scientists. | The team who spent 10 years working on the project included physicists, pharmacologists, clinicians and cellular scientists. |
You can see the common pathway of death and suffering is heart failure Sir Magdi Yacoub Researchers will see their achievement as a major step towards growing entire organs for transplant. | |
Stem cells have the potential to turn into many different types of cell. | Stem cells have the potential to turn into many different types of cell. |
Many scientists believe it should be possible to harness the cells' ability to grow into different tissues to repair damage and treat disease. | |
Previously, scientists have grown tendons, cartilages and bladders, which are all less complex. | Previously, scientists have grown tendons, cartilages and bladders, which are all less complex. |
Sir Magdi, professor of cardiac surgery at Imperial College London, had been working on ways to address a shortage of donated hearts for patients. | Sir Magdi, professor of cardiac surgery at Imperial College London, had been working on ways to address a shortage of donated hearts for patients. |
He said he hoped that soon an entire heart could be grown from stem cells. | He said he hoped that soon an entire heart could be grown from stem cells. |
He added: "It is an ambitious project but not impossible. If you want me to guess I'd say 10 years." | |
His team extracted stem cells from bone marrow and cultivated them into heart valve cells. | His team extracted stem cells from bone marrow and cultivated them into heart valve cells. |
After they were placed in scaffolds formed from collagen, 3cm-wide discs of heart valve tissue were formed. | After they were placed in scaffolds formed from collagen, 3cm-wide discs of heart valve tissue were formed. |
Later in the year, these will be implanted into animals such as sheep or pigs to see how well they fare. | Later in the year, these will be implanted into animals such as sheep or pigs to see how well they fare. |
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