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'Anti-Aids gel' trial is stopped | 'Anti-Aids gel' trial is stopped |
(about 4 hours later) | |
Clinical trials of a new drug designed to help prevent women contracting the Aids virus have been stopped. | Clinical trials of a new drug designed to help prevent women contracting the Aids virus have been stopped. |
The World Health Organization said the drug, which uses a microbicidal gel, did not help the women and made them more vulnerable. | |
The tests were carried out on more than 1,300 women in South Africa, Benin, Uganda and India. | The tests were carried out on more than 1,300 women in South Africa, Benin, Uganda and India. |
The WHO and the United Nations Aids agency said it was not clear why the product did not work. | The WHO and the United Nations Aids agency said it was not clear why the product did not work. |
A similar test in Nigeria has also been halted but trials of three other microbicides are still continuing. | A similar test in Nigeria has also been halted but trials of three other microbicides are still continuing. |
The cellulose sulfate gel, based on seaweed and made by Canadian company Polydex Pharmaceuticals, was supposed to release an active ingredient designed to kill HIV during sexual intercourse. | |
"This is a disappointing and unexpected setback in the search for a safe and effective microbicide that can be used by women to protect themselves against HIV infection," said WHO and UNAids in a joint statement. | "This is a disappointing and unexpected setback in the search for a safe and effective microbicide that can be used by women to protect themselves against HIV infection," said WHO and UNAids in a joint statement. |
Around 30 women had contracted HIV since the trial started in 2005, the AFP news agency quotes study co-ordinator Tim Farley as saying. | Around 30 women had contracted HIV since the trial started in 2005, the AFP news agency quotes study co-ordinator Tim Farley as saying. |
Scientists had hoped that microbicides could have a major impact in the fight against Aids, especially in Africa, where women bear the brunt of the disease. | Scientists had hoped that microbicides could have a major impact in the fight against Aids, especially in Africa, where women bear the brunt of the disease. |
They are being developed because it is often difficult for women to insist that men use condoms during sex. | They are being developed because it is often difficult for women to insist that men use condoms during sex. |