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'Anti-Aids gel' trial is stopped 'Anti-Aids gel' trial is stopped
(about 4 hours later)
Clinical trials of a new drug designed to help prevent women contracting the Aids virus have been stopped.Clinical trials of a new drug designed to help prevent women contracting the Aids virus have been stopped.
The World Health Organisation said the drug - involving a gel known as a microbicide - did not help the women and made them more vulnerable. The World Health Organization said the drug, which uses a microbicidal gel, did not help the women and made them more vulnerable.
The tests were carried out on more than 1,300 women in South Africa, Benin, Uganda and India.The tests were carried out on more than 1,300 women in South Africa, Benin, Uganda and India.
The WHO and the United Nations Aids agency said it was not clear why the product did not work.The WHO and the United Nations Aids agency said it was not clear why the product did not work.
A similar test in Nigeria has also been halted but trials of three other microbicides are still continuing.A similar test in Nigeria has also been halted but trials of three other microbicides are still continuing.
The cellulose sulfate gel, based on seaweed and made by Canadian company Polydex Pharmaceuticals was supposed to release an active ingredient designed to kill HIV during sexual intercourse. The cellulose sulfate gel, based on seaweed and made by Canadian company Polydex Pharmaceuticals, was supposed to release an active ingredient designed to kill HIV during sexual intercourse.
"This is a disappointing and unexpected setback in the search for a safe and effective microbicide that can be used by women to protect themselves against HIV infection," said WHO and UNAids in a joint statement."This is a disappointing and unexpected setback in the search for a safe and effective microbicide that can be used by women to protect themselves against HIV infection," said WHO and UNAids in a joint statement.
Around 30 women had contracted HIV since the trial started in 2005, the AFP news agency quotes study co-ordinator Tim Farley as saying.Around 30 women had contracted HIV since the trial started in 2005, the AFP news agency quotes study co-ordinator Tim Farley as saying.
Scientists had hoped that microbicides could have a major impact in the fight against Aids, especially in Africa, where women bear the brunt of the disease.Scientists had hoped that microbicides could have a major impact in the fight against Aids, especially in Africa, where women bear the brunt of the disease.
They are being developed because it is often difficult for women to insist that men use condoms during sex.They are being developed because it is often difficult for women to insist that men use condoms during sex.