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Urgent recall of contaminated antibiotic powder Urgent recall of contaminated antibiotic powder
(4 months later)
The recall affects some batches of "Targocid 200mg powder for solution for injection/infusion or oral solution"The recall affects some batches of "Targocid 200mg powder for solution for injection/infusion or oral solution"
Some batches of an antibiotic medicine called teicoplanin (brand name Targocid) are being urgently recalled in the UK because of possible contamination.Some batches of an antibiotic medicine called teicoplanin (brand name Targocid) are being urgently recalled in the UK because of possible contamination.
The two affected batches are labelled 0J25D1 and 0J25D2, say safety experts.The two affected batches are labelled 0J25D1 and 0J25D2, say safety experts.
Patients and prescribers are being asked to check packs and stop using the medicine if it has either batch number.Patients and prescribers are being asked to check packs and stop using the medicine if it has either batch number.
Four patients so far have suffered high fevers just hours after being given a dose from these batches.Four patients so far have suffered high fevers just hours after being given a dose from these batches.
Other products containing teicoplanin are not affected by the recall.Other products containing teicoplanin are not affected by the recall.
The Medicines and Healthcare products Regulatory Agency (MHRA) says the two batches of Targocid 200mg powder for making a solution to take as an injection, by infusion or by mouth, were found to contain high levels of bacterial endotoxins - a toxic compound found in bacterial cell walls that can cause inflammation-related symptoms, high fever and, in very serious cases, septic shock.The Medicines and Healthcare products Regulatory Agency (MHRA) says the two batches of Targocid 200mg powder for making a solution to take as an injection, by infusion or by mouth, were found to contain high levels of bacterial endotoxins - a toxic compound found in bacterial cell walls that can cause inflammation-related symptoms, high fever and, in very serious cases, septic shock.
Dr Alison Cave, MHRA Chief Safety Officer, advised: "It is vitally important that you check the labels of your Targocid 200mg powder and if the batch number is 0J25D1 or 0J25D2, you should stop using the medicine and seek immediate medical advice from a healthcare professional. If you are unsure which batch you have been given to use at home, please seek medical advice.Dr Alison Cave, MHRA Chief Safety Officer, advised: "It is vitally important that you check the labels of your Targocid 200mg powder and if the batch number is 0J25D1 or 0J25D2, you should stop using the medicine and seek immediate medical advice from a healthcare professional. If you are unsure which batch you have been given to use at home, please seek medical advice.
"Your healthcare professional will arrange a new prescription for you and answer any questions you may have.""Your healthcare professional will arrange a new prescription for you and answer any questions you may have."
If you are currently on Targocid and have any of the following symptoms, you should seek medical advice:If you are currently on Targocid and have any of the following symptoms, you should seek medical advice:
a high temperature (fever) or low body temperaturea high temperature (fever) or low body temperature
chills and shiveringchills and shivering
cold, clammy and pale or mottled skincold, clammy and pale or mottled skin
a fast heartbeata fast heartbeat
fast breathingfast breathing
severe breathlessnesssevere breathlessness
severe muscle painsevere muscle pain
feeling dizzy or faintfeeling dizzy or faint
a change in mental state - such as confusion or disorientationa change in mental state - such as confusion or disorientation
loss of consciousnessloss of consciousness
slurred speechslurred speech
nausea and vomitingnausea and vomiting
diarrhoeadiarrhoea
feeling increasingly unwellfeeling increasingly unwell
Targocid is an antibiotic used to treat a wide range of infections. For most patients, this product is administered by healthcare professionals directly in hospitals, but some patients are given it to take at home.Targocid is an antibiotic used to treat a wide range of infections. For most patients, this product is administered by healthcare professionals directly in hospitals, but some patients are given it to take at home.
Patients using generic brands of this product and unaffected batches of Targocid do not need to be concerned.Patients using generic brands of this product and unaffected batches of Targocid do not need to be concerned.
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