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Coronavirus Live Updates: U.S. Sends Two Million Hydroxychloroquine Doses to Brazil | Coronavirus Live Updates: U.S. Sends Two Million Hydroxychloroquine Doses to Brazil |
(32 minutes later) | |
The United States has delivered two million doses of a malaria drug to Brazil for use in the fight against the coronavirus pandemic, and the two countries are embarking on a joint research effort to study whether the drug is safe and effective for the prevention and early treatment of Covid-19, the White House announced Sunday. | The United States has delivered two million doses of a malaria drug to Brazil for use in the fight against the coronavirus pandemic, and the two countries are embarking on a joint research effort to study whether the drug is safe and effective for the prevention and early treatment of Covid-19, the White House announced Sunday. |
The White House announcement comes after months of controversy over the drug, hydroxychloroquine, which President Trump has aggressively promoted, despite a lack of scientific evidence of its effectiveness as a treatment for Covid-19. Mr. Trump stunned public health experts recently by saying he was taking a two-week course of the medicine. | The White House announcement comes after months of controversy over the drug, hydroxychloroquine, which President Trump has aggressively promoted, despite a lack of scientific evidence of its effectiveness as a treatment for Covid-19. Mr. Trump stunned public health experts recently by saying he was taking a two-week course of the medicine. |
The donated doses will be used as a prophylactic “to help defend” Brazil’s nurses, doctors and health care professionals against infection, and will also be used as a therapeutic to treat Brazilians who become infected, the White House said. | The donated doses will be used as a prophylactic “to help defend” Brazil’s nurses, doctors and health care professionals against infection, and will also be used as a therapeutic to treat Brazilians who become infected, the White House said. |
Hydroxychloroquine is widely used for the prevention of malaria and for treatment of certain autoimmune diseases including rheumatoid arthritis and lupus, and many doctors consider it safe. But the Food and Drug Administration has warned that it can cause heart arrhythmias in some patients, and the debate over its use in the coronavirus pandemic has been politically fraught. | Hydroxychloroquine is widely used for the prevention of malaria and for treatment of certain autoimmune diseases including rheumatoid arthritis and lupus, and many doctors consider it safe. But the Food and Drug Administration has warned that it can cause heart arrhythmias in some patients, and the debate over its use in the coronavirus pandemic has been politically fraught. |
Early research in Brazil and New York suggested that it could be linked to a higher number of deaths among hospitalized patients. More recently, a review of a hospital database published by the influential medical journal, The Lancet, concluded that treating people who have Covid-19 with chloroquine and hydroxychloroquine did not help and might have increased the risk of abnormal heart rhythms and death. | Early research in Brazil and New York suggested that it could be linked to a higher number of deaths among hospitalized patients. More recently, a review of a hospital database published by the influential medical journal, The Lancet, concluded that treating people who have Covid-19 with chloroquine and hydroxychloroquine did not help and might have increased the risk of abnormal heart rhythms and death. |
But last week, more than 100 scientists and clinicians questioned the authenticity of that database. Some researchers say hydroxychloroquine does show promise as a possible prophylactic or treatment in the early stages of Covid-19, and a number of clinical trials — including one conducted by the National Institute for Allergy and Infectious Diseases — are trying to answer those questions. Amid the uproar, experts say, legitimate research has suffered. | But last week, more than 100 scientists and clinicians questioned the authenticity of that database. Some researchers say hydroxychloroquine does show promise as a possible prophylactic or treatment in the early stages of Covid-19, and a number of clinical trials — including one conducted by the National Institute for Allergy and Infectious Diseases — are trying to answer those questions. Amid the uproar, experts say, legitimate research has suffered. |
Mass protests against police brutality that have brought thousands of people out of their homes and onto the streets in cities across America are raising the specter of new coronavirus outbreaks, prompting political leaders, physicians and public health experts to warn that the crowds could cause a surge in cases. | Mass protests against police brutality that have brought thousands of people out of their homes and onto the streets in cities across America are raising the specter of new coronavirus outbreaks, prompting political leaders, physicians and public health experts to warn that the crowds could cause a surge in cases. |
While many political leaders affirmed the right of protesters to express themselves, they urged the demonstrators to wear face masks and maintain social distancing, both to protect themselves and to prevent further community spread of the virus. | While many political leaders affirmed the right of protesters to express themselves, they urged the demonstrators to wear face masks and maintain social distancing, both to protect themselves and to prevent further community spread of the virus. |
More than 100,000 Americans have already died of Covid-19, the disease caused by the new coronavirus. People of color have been particularly hard hit, with rates of hospitalizations and deaths among black Americans far exceeding those of whites. | More than 100,000 Americans have already died of Covid-19, the disease caused by the new coronavirus. People of color have been particularly hard hit, with rates of hospitalizations and deaths among black Americans far exceeding those of whites. |
Some infectious disease experts were reassured by the fact that the protests were held outdoors, saying the open air settings could mitigate the risk of transmission. In addition, many of the demonstrators were wearing masks, and in some places, they appeared to be avoiding clustering too closely. | Some infectious disease experts were reassured by the fact that the protests were held outdoors, saying the open air settings could mitigate the risk of transmission. In addition, many of the demonstrators were wearing masks, and in some places, they appeared to be avoiding clustering too closely. |
“The outdoor air dilutes the virus and reduces the infectious dose that might be out there, and if there are breezes blowing, that further dilutes the virus in the air,” said Dr. William Schaffner, an infectious disease expert at Vanderbilt University. “There was literally a lot of running around, which means they’re exhaling more profoundly, but also passing each other very quickly.” | “The outdoor air dilutes the virus and reduces the infectious dose that might be out there, and if there are breezes blowing, that further dilutes the virus in the air,” said Dr. William Schaffner, an infectious disease expert at Vanderbilt University. “There was literally a lot of running around, which means they’re exhaling more profoundly, but also passing each other very quickly.” |
Jimmy Mills’s barbershop in Midtown Minneapolis was one of many small, black-owned businesses that have struggled to survive the pandemic. But Mr. Mills was hopeful because, after two months of shut down, he was set to reopen next week. | Jimmy Mills’s barbershop in Midtown Minneapolis was one of many small, black-owned businesses that have struggled to survive the pandemic. But Mr. Mills was hopeful because, after two months of shut down, he was set to reopen next week. |
Then early on Friday, the working-class neighborhood where Mr. Mills has cut hair for 12 years went up in flames as chaotic protests over the death of George Floyd and police killings of African-Americans engulfed Minneapolis and cities across the country. | Then early on Friday, the working-class neighborhood where Mr. Mills has cut hair for 12 years went up in flames as chaotic protests over the death of George Floyd and police killings of African-Americans engulfed Minneapolis and cities across the country. |
“To have corona, and then this — it’s like a gut shot,” Mr. Mills, 56, said. | “To have corona, and then this — it’s like a gut shot,” Mr. Mills, 56, said. |
With more than 200 businesses damaged or destroyed in the unrest, Mr. Noor said he was worried about new waves of foreclosures, job losses and business failures. | With more than 200 businesses damaged or destroyed in the unrest, Mr. Noor said he was worried about new waves of foreclosures, job losses and business failures. |
“Many people who are poor who didn’t have much, this devastation will really impact them,” Mr. Noor said. | “Many people who are poor who didn’t have much, this devastation will really impact them,” Mr. Noor said. |
Even before the pandemic, the Midtown neighborhood, where buildings were burned, damaged and looted, had been trying to rebuild itself after years of economic hardship. The area is in a historically segregated part of town where some residents had felt neglected. A railway was repurposed into a bike and walking trail that runs through the neighborhood. The Midtown Global Market had sprung up, attracting diners and shoppers to its Hmong, Indian, Moroccan and other international food and crafts. | Even before the pandemic, the Midtown neighborhood, where buildings were burned, damaged and looted, had been trying to rebuild itself after years of economic hardship. The area is in a historically segregated part of town where some residents had felt neglected. A railway was repurposed into a bike and walking trail that runs through the neighborhood. The Midtown Global Market had sprung up, attracting diners and shoppers to its Hmong, Indian, Moroccan and other international food and crafts. |
But now, next door to Mr. Mills, the barber, a dollar store and beauty-supply shop have been burned to rubble. The front windows of Mr. Mills’s barbershop were smashed, and looters stole his televisions, video equipment and his clippers. | But now, next door to Mr. Mills, the barber, a dollar store and beauty-supply shop have been burned to rubble. The front windows of Mr. Mills’s barbershop were smashed, and looters stole his televisions, video equipment and his clippers. |
With the power out, water seeping across the floor and phalanxes of police officers and National Guard troops blockading his neighborhood, he does not know when his J-Klips barbershop might reopen. | With the power out, water seeping across the floor and phalanxes of police officers and National Guard troops blockading his neighborhood, he does not know when his J-Klips barbershop might reopen. |
The Paycheck Protection Program, the federal government’s ambitious effort to keep workers at small businesses off the unemployment rolls through the worst of the pandemic, has provided a financial safety net to more than four million companies. | The Paycheck Protection Program, the federal government’s ambitious effort to keep workers at small businesses off the unemployment rolls through the worst of the pandemic, has provided a financial safety net to more than four million companies. |
For many, the money was a lifeline. It let a trucking company keep paying drivers who would otherwise have been laid off and gave a group of therapists time to adjust to telemedicine and connect with new clients. | For many, the money was a lifeline. It let a trucking company keep paying drivers who would otherwise have been laid off and gave a group of therapists time to adjust to telemedicine and connect with new clients. |
But the pandemic’s devastation continues. Many cities are still shut, consumers’ habits have changed and recharging the economy may take years. Small companies, which employ nearly half of America’s workers who don’t work in government, typically have thin margins and scant savings. Some fear they won’t survive without further help. | But the pandemic’s devastation continues. Many cities are still shut, consumers’ habits have changed and recharging the economy may take years. Small companies, which employ nearly half of America’s workers who don’t work in government, typically have thin margins and scant savings. Some fear they won’t survive without further help. |
Even for those who received help, the program’s rollout was messy and chaotic, and Congress is arguing over proposed changes. The program offered small companies a loan that would be converted to a grant if they used most of the money for eight weeks of payroll. The earliest loan recipients are near the end of their eight-week relief period. Some fear they won’t survive without further help. | Even for those who received help, the program’s rollout was messy and chaotic, and Congress is arguing over proposed changes. The program offered small companies a loan that would be converted to a grant if they used most of the money for eight weeks of payroll. The earliest loan recipients are near the end of their eight-week relief period. Some fear they won’t survive without further help. |
With an intensity of flavor to match their color, the big, bright-red prawns caught off Spain’s eastern coast are the kind of delicacy that someone might eat once or twice in a year and remember fondly for the rest of it. | With an intensity of flavor to match their color, the big, bright-red prawns caught off Spain’s eastern coast are the kind of delicacy that someone might eat once or twice in a year and remember fondly for the rest of it. |
Around Christmas, when they are often a highlight of restaurants’ holiday menus, the wholesale price at the daily fish auctions in ports like that of Llançà, in Catalonia, would be up to 100 euros a kilogram. That’s about $50 a pound. In mid-March, before Spain declared its coronavirus state of emergency, they fetched around €70 a kilogram. | Around Christmas, when they are often a highlight of restaurants’ holiday menus, the wholesale price at the daily fish auctions in ports like that of Llançà, in Catalonia, would be up to 100 euros a kilogram. That’s about $50 a pound. In mid-March, before Spain declared its coronavirus state of emergency, they fetched around €70 a kilogram. |
In Llançà this month, a kilogram went for €36. | In Llançà this month, a kilogram went for €36. |
More than 90 percent of the catch would usually be earmarked for restaurants. With dining rooms closed, that top-end market has disappeared, and the prawns are being picked up at vastly reduced prices by fishmongers who serve a much broader clientele than the elite customers of Spain’s best restaurants. | More than 90 percent of the catch would usually be earmarked for restaurants. With dining rooms closed, that top-end market has disappeared, and the prawns are being picked up at vastly reduced prices by fishmongers who serve a much broader clientele than the elite customers of Spain’s best restaurants. |
For those working on fishing boats trawling the seabed in search of the prawns — 12 hours at sea can yield just a dozen kilograms or so — the only consolation has been that oil prices have also collapsed, allowing them to use their boats without spending so much on gas. | For those working on fishing boats trawling the seabed in search of the prawns — 12 hours at sea can yield just a dozen kilograms or so — the only consolation has been that oil prices have also collapsed, allowing them to use their boats without spending so much on gas. |
“The question is whether people will return in large numbers to the restaurants before the oil prices rise again,” said Josep Garriga, 71, who has officially retired but who still enjoys prawn fishing alongside his son, Jaume, who has taken over the captaincy of their family boat. “Everything has become like the day-to-day uncertainty of fishing, where you always hope for a good catch but never start with anything guaranteed.” | “The question is whether people will return in large numbers to the restaurants before the oil prices rise again,” said Josep Garriga, 71, who has officially retired but who still enjoys prawn fishing alongside his son, Jaume, who has taken over the captaincy of their family boat. “Everything has become like the day-to-day uncertainty of fishing, where you always hope for a good catch but never start with anything guaranteed.” |
Nicaragua is one of the last countries to resist adopting strict measures to curb the spread of the virus. It never closed its schools. It did not shutter businesses. Throughout the pandemic, the government not only allowed mass events — it organized them. | Nicaragua is one of the last countries to resist adopting strict measures to curb the spread of the virus. It never closed its schools. It did not shutter businesses. Throughout the pandemic, the government not only allowed mass events — it organized them. |
Now there are signs everywhere that the virus is raging across the country, though the government insists it has the situation under control. | Now there are signs everywhere that the virus is raging across the country, though the government insists it has the situation under control. |
Long lines have formed at hospitals, and pharmacies have run out of basic medicines. Families of people who die of respiratory illnesses are being forced to hold “express burials” at all hours of the night, for fear of contagion. | Long lines have formed at hospitals, and pharmacies have run out of basic medicines. Families of people who die of respiratory illnesses are being forced to hold “express burials” at all hours of the night, for fear of contagion. |
Health organizations are struggling to get accurate case numbers. Testing is limited and controlled by the government. Doctors and activists are bracing for disaster, just two years after antigovernment uprisings against President Daniel Ortega turned violent. | Health organizations are struggling to get accurate case numbers. Testing is limited and controlled by the government. Doctors and activists are bracing for disaster, just two years after antigovernment uprisings against President Daniel Ortega turned violent. |
Facing withering criticism, the government released a report last Monday stating that critics were trying to sow chaos, and that the vast majority of people in the country, the second-poorest in the hemisphere, could not afford to lose work under a strict lockdown. | Facing withering criticism, the government released a report last Monday stating that critics were trying to sow chaos, and that the vast majority of people in the country, the second-poorest in the hemisphere, could not afford to lose work under a strict lockdown. |
Elena Cano said her 46-year-old son, Camilo Meléndez, the facilities manager at the National Assembly building, died on May 19 from “unusual severe pneumonia,” after trying to get medical care several times. | Elena Cano said her 46-year-old son, Camilo Meléndez, the facilities manager at the National Assembly building, died on May 19 from “unusual severe pneumonia,” after trying to get medical care several times. |
“The whole world has to understand the truth of the crime that our government is committing,” she said. | “The whole world has to understand the truth of the crime that our government is committing,” she said. |
In communities from the Deep South to California, congregations that had been sequestered for months ventured forth at a social distance on Sunday in search of comfort, prayer and political expression. | In communities from the Deep South to California, congregations that had been sequestered for months ventured forth at a social distance on Sunday in search of comfort, prayer and political expression. |
With their sick and elderly at home and their nation wracked by the pandemic, evangelical congregations across California violated state health rules in the name of unity. | With their sick and elderly at home and their nation wracked by the pandemic, evangelical congregations across California violated state health rules in the name of unity. |
“Outside the confines of these walls we hear the sound of a very broken world,” Samuel Rodriguez, the pastor of New Season Christian Worship Center in Sacramento, said. | “Outside the confines of these walls we hear the sound of a very broken world,” Samuel Rodriguez, the pastor of New Season Christian Worship Center in Sacramento, said. |
At least a dozen evangelical churches in California made a coordinated return to church timed to Pentecost, a holy day particularly tied to fundamentalist worship. Some in that group were also seeking to pressure the state’s Democratic governor, Gavin Newsom, into dropping a 100-person cap on church attendance that the state had enacted to curb the spread of the disease. | At least a dozen evangelical churches in California made a coordinated return to church timed to Pentecost, a holy day particularly tied to fundamentalist worship. Some in that group were also seeking to pressure the state’s Democratic governor, Gavin Newsom, into dropping a 100-person cap on church attendance that the state had enacted to curb the spread of the disease. |
Supporters acknowledged the legal and health risks, but said their congregants’ spiritual health would suffer if they delayed their return to public worship. | Supporters acknowledged the legal and health risks, but said their congregants’ spiritual health would suffer if they delayed their return to public worship. |
“It’s been terrible, an unimaginable tide of grief,” said the Rev. W. Franklyn Richardson, the senior pastor at Grace Baptist Church in Mount Vernon, N.Y., said of the moment. Mr. Richardson, who is African-American, noted that during the worst of the pandemic, he was making three to five condolence calls a day. | “It’s been terrible, an unimaginable tide of grief,” said the Rev. W. Franklyn Richardson, the senior pastor at Grace Baptist Church in Mount Vernon, N.Y., said of the moment. Mr. Richardson, who is African-American, noted that during the worst of the pandemic, he was making three to five condolence calls a day. |
Still, he said, the church has not, and cannot, abdicate its central role in pushing for positive change. “I think the church has to help make sure it is a wake up call,” he said of the unrest. “The church has had to be a safety net for a society that has ignored the community.” | Still, he said, the church has not, and cannot, abdicate its central role in pushing for positive change. “I think the church has to help make sure it is a wake up call,” he said of the unrest. “The church has had to be a safety net for a society that has ignored the community.” |
Customer service representatives, even on the best of days, typically field a lot of complaints — missing deliveries, unsatisfied customers and other gripes. But these days, with people grappling with financial insecurity, separation from their friends and family, and uncertainty, the tone has changed. Rather than viewing calls as a form of drudgery, some people seem to relish having a person on the other end of the line to talk with. | |
Sensing the shifting need, and wanting to make use of customer service representatives whose call volume was down, Zappos, the online merchant best known for its shoes, in April revamped its customer service line: People could call just to chat — about their future travel plans, Netflix shows or anything on their minds. | |
“Sure, we take orders and process returns, but we’re also great listeners,” Zappos said in a statement on its website. “Searching for flour to try that homemade bread recipe? We’re happy to call around and find grocery stores stocked with what you need.” | |
People have called to have conversations about their life stories. Single parents at home with small children have called, grateful to speak with another adult. Teenagers have called asking for homework help. | |
But the new line is good for more than helping to stock toilet paper. | |
In mid-April, around the time when coronavirus patients were filling New York City hospitals and equipment was in short supply, David F. Putrino, the director of rehabilitation innovation for the Mount Sinai Health System, reached out to Zappos looking for pulse oximeters, devices that indicate blood oxygen level and heart rate. | |
The devices were sold out or on back-order everywhere he looked. To his amazement, Zappos was able to locate the devices. Within days, the company had shipped 500 oximeters to Mount Sinai — and later donated an additional 50. | |
“It was, like, unbelievable from our perspective,” he said. | |
Reporting was contributed by Roni Caryn Rabin, Raphael Minder, Jack Healy, Dionne Searcey, Stacy Cowley, Antonio de Luca, Rick Rojas, Stacy Cowley, Dave Taft and Umi Syam. | Reporting was contributed by Roni Caryn Rabin, Raphael Minder, Jack Healy, Dionne Searcey, Stacy Cowley, Antonio de Luca, Rick Rojas, Stacy Cowley, Dave Taft and Umi Syam. |