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| Scientists clone from frozen mice | Scientists clone from frozen mice |
| (about 8 hours later) | |
| Japanese scientists have managed to create clones from the bodies of mice which have been frozen for 16 years. | Japanese scientists have managed to create clones from the bodies of mice which have been frozen for 16 years. |
| Cloning had so far only been achieved using live donor cells and transferring their DNA to recipient eggs. | Cloning had so far only been achieved using live donor cells and transferring their DNA to recipient eggs. |
| Experts believed that using thawed frozen cells would not be possible because of ice damage to the DNA. | Experts believed that using thawed frozen cells would not be possible because of ice damage to the DNA. |
| The scientists in Kobe, Japan, said the technique raised the possibility of recreating extinct creatures such as mammoths from their frozen remains. | The scientists in Kobe, Japan, said the technique raised the possibility of recreating extinct creatures such as mammoths from their frozen remains. |
| Many of the successful clones since Dolly the sheep was born in 1996 have been created by a method where the nucleus of a cell has been removed, placed in an empty egg and kick-started into replicating by chemicals or electricity. | |
| Frozen bodies | Frozen bodies |
| The Japanese research suggests it is not the case that frozen cells would be unusable because the formation of ice would be likely to damage the DNA they contained. | The Japanese research suggests it is not the case that frozen cells would be unusable because the formation of ice would be likely to damage the DNA they contained. |
| The scientists successfully created clones using the brain cells from mice that had been frozen at -20C. | The scientists successfully created clones using the brain cells from mice that had been frozen at -20C. |
| The frozen bodies of mammoths have been found dating back 40,000 years. | The frozen bodies of mammoths have been found dating back 40,000 years. |
| However, the researchers warned that the lack of suitable species for recipient eggs and surrogate mothers were "major problems" for the technique to be used for extinct or endangered animals. | However, the researchers warned that the lack of suitable species for recipient eggs and surrogate mothers were "major problems" for the technique to be used for extinct or endangered animals. |
| The work at Kobe's Centre for Developmental Biology was reported in the journal Proceedings of the National Academy of Sciences (PNAS). | The work at Kobe's Centre for Developmental Biology was reported in the journal Proceedings of the National Academy of Sciences (PNAS). |